Twenty-one specimens of Upogegia vasquezi Ncoc-Ho, 1989 were collected from the sandy mud shores of Carenero, on La Tortuga Island by means a yabby pump, a first record of this species in Venezuelan waters. Upogebia vasquezi is characterized: as follows: rostrum short; postocular spine present; first antennal article with ventral subdistal spine; abdominal sternites unarmed; coxa of first pereiopod with small spine on distomesial margin, chelae with spines in ventromesial, coxa of second pereiopod with small spine on distomesial margin, merus with a single proximal spine on ventral margin; merus of third pereiopod with 4 or 5 proximal spines on ventral margin; and merus of both fourth and fifth pereiopods spineless. Although this species is widely distributed in the Western Atlantic, it had not been recorded for Venezuela until now.